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Panama City Panama

Itinerary · Central America · 10 days · Easy

Ocean to Ocean in Ten Days

Panama City→Miraflores Locks→Soberanía NP→Guna Yala→Boquete→Volcán Barú+1 stops

PanamaFrom €1,330 / $1,436
Duration
10 days
Countries
Panama
Difficulty
Easy
Est. budget
€1,330 / $1,436

A country you can cross before lunch, used properly: the canal and the restored colonial quarter, rainforest twenty minutes from a skyline, the Guna archipelago on the Caribbean, and coffee country in the western highlands.

→Miraflores and the Agua Clara locks
→Casco Viejo
→Guna Yala islands
→Boquete coffee and cloud forest
Day
01

Panama City

Panama CityGetting here: Arrival flightStay: Casco Viejo hotel

Land and go straight to Casco Viejo - the walled quarter rebuilt after Henry Morgan burned the original city in 1671, restored over the last two decades and now a UNESCO site of plazas, balconies and rooftop bars looking back at the skyline across the bay.

Taxi or tour
Day
02

The locks

Miraflores LocksGetting here: Taxi or tourStay: Casco Viejo hotel

Miraflores on the Pacific side has the viewing platform and the museum; Agua Clara on the Caribbean side shows the 2016 expansion locks with their water-saving basins and is the better engineering visit. Check the transit schedule before going - the platform is only worth it when a ship is in the chamber.

Early transfer
Day
03

Rainforest before breakfast

Soberanía NPGetting here: Early transferStay: Casco Viejo hotel

Pipeline Road in Soberanía National Park, forty minutes from the financial district, has recorded some of the highest single-day bird counts anywhere on earth. Go at dawn with a guide. Afternoon: the ruins of Panamá Viejo, the city Morgan destroyed.

4x4 + boat

Guna Yala

Day 4–5 · 2 days
Day
04

To Guna Yala

Getting here: 4x4 + boatStay: Guna island cabaña

A pre-dawn 4x4 over the cordillera to Cartí, then a boat out to the islands. Guna Yala is autonomous territory, governed by the Guna since an armed revolution in 1925; you enter on their terms, pay their fees, and stay in community-run lodging.

Day
05

Islands

Getting here: Small boat between islandsStay: Guna island cabaña

Sand, palms, reef and very little else - no resorts, limited electricity, and molas for sale made by the women who sew them. Rising sea levels are forcing the relocation of some communities to the mainland, and that conversation is happening while you visit.

Flight or night bus + shuttle

Boquete

Day 6–7 · 2 days
Day
06

West to Boquete

Getting here: Flight or night bus + shuttleStay: Boquete lodge

Back to the city and fly or take the overnight bus to David, then up into the Chiriquí highlands. Boquete sits at 1,200 metres under Volcán Barú and the temperature drops by ten degrees, which is the point.

Day
07

Coffee and quetzals

Stay: Boquete lodge

A farm tour on the slopes where the geisha varietal - the one that regularly sets world auction records - is grown, followed by a cupping. Afternoon on the Sendero Los Quetzales, a cloud-forest trail where the bird is genuinely findable in season.

Guided hike or 4x4
Day
08

Volcán Barú, or the hot springs

Volcán BarúGetting here: Guided hike or 4x4Stay: Boquete lodge

Barú is 3,475 metres and on the rare clear morning you can see both oceans from the summit - a brutal overnight hike or a 4x4 up the track. The gentler alternative is the Caldera hot springs and the lost-waterfalls trail.

Shuttle + water taxi

Bocas del Toro

Day 9–10 · 2 days
Day
09

Bocas del Toro

Getting here: Shuttle + water taxiStay: Bocas overwater guesthouse

Over the Talamanca range to the Caribbean and a boat to the archipelago: Afro-Caribbean, English-Creole speaking, built on stilts over the water, with reef and mangrove and a very different rhythm from anywhere else in the country.

Day
10

Out

Getting here: Domestic flight + departure

Fly Bocas to Panama City for the international connection. Domestic schedules are tight - do not plan a same-day long-haul departure without a buffer.

Good to know

Panama uses the US dollar (locally called the balboa for coins). Cards work widely, which is not true of every neighbour.

Guna Yala requires paying community entry fees and, in most cases, arranging the 4x4 and boat as a package. It is not a place to improvise, and photography of people requires asking.

The Darién Gap is not a trekking route. It is currently one of the most dangerous irregular migration corridors in the world and should not be attempted.

Shorter or longer?

1 week

City, canal, Soberanía and Guna Yala - no western highlands leg.

+ Pearl Islands

Add three days on Contadora or Isla San José in the Pacific, an hour by air from the capital.

+ Costa Rica

Cross west from Bocas at Sixaola into the Costa Rican Caribbean.

Practical guide

Visa check for this route

Panama

Budget

Accommodation (9 nights)€480 / $518
Food & drink€260 / $281
Transport & internal flights€350 / $378
Guides, fees & tours€240 / $259
Total€1,330 / $1,436

Mid-range · per person · sharing a double room. Excludes international flights - they depend on where you fly from.

Editorial estimates · checked August 2026

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